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Filtered Search Results
eMolecules Ambeed / 2-Phenylcyclopropanecarboxylic acid / 250mg / 490538655 / A226797 / / 5685-38-1 / MFCD00066860 / 162.188 / C10H10O2
Ambeed / 2-Phenylcyclopropanecarboxylic acid / 250mg / 490538655 / A226797 / / 5685-38-1 / MFCD00066860 / 162.188 / C10H10O2
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eMolecules Ambeed / 2-Hydrazinyl-4-methylpyridine / 250mg / 572144414 / A187550 / / 4931-00-4 / MFCD09863246 / 123.159 / C6H9N3
Ambeed / 2-Hydrazinyl-4-methylpyridine / 250mg / 572144414 / A187550 / / 4931-00-4 / MFCD09863246 / 123.159 / C6H9N3
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules AstaTech / 26-DIHYDROXY-4-METHYLBENZOIC ACID / 1g / 718083507 / D90113 / 95.000 / 480-67-1 / MFCD00184686 / 168.148 / C8H8O4
AstaTech / 26-DIHYDROXY-4-METHYLBENZOIC ACID / 1g / 718083507 / D90113 / 95.000 / 480-67-1 / MFCD00184686 / 168.148 / C8H8O4
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eMolecules Ambeed / 444-Nitrilotris(([11-biphenyl]-35-dicarboxylic acid)) / 100mg / 633659299 / A1154790 / / 1347748-59-7 / [null] / 737.673 / C42H27NO12
Ambeed / 444-Nitrilotris(([11-biphenyl]-35-dicarboxylic acid)) / 100mg / 633659299 / A1154790 / / 1347748-59-7 / [null] / 737.673 / C42H27NO12
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eMolecules Ambeed / 2-Morpholinobenzaldehyde / 250mg / 525194117 / A352413 / / 58028-76-5 / MFCD00662562 / 191.230 / C11H13NO2
Ambeed / 2-Morpholinobenzaldehyde / 250mg / 525194117 / A352413 / / 58028-76-5 / MFCD00662562 / 191.230 / C11H13NO2
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Medchemexpress LLC Zeteletinib | 2216753-97-6 | 98.3% | 500.47 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Zeteletinib is an orally active, selective RET kinase inhibitor with nanomolar potency against RET and over 300-fold selectivity against VEGFR2. It shows exquisite potency for the wild-type RET, RETV804M/L gatekeeper mutants, and the most common oncogenic RET mutation M918T. This compound exhibits potent antitumor activity and is intended for research use only.
- Orally active and selective RET kinase inhibitor.
- Nanomolar potency against RET.
- Over 300-fold selectivity against VEGFR2.
- Potent against wild-type RET, RETV804M/L gatekeeper mutants, and M918T oncogenic RET mutation.
- Exhibits potent antitumor activity.
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Medchemexpress LLC Bixin | 6983-79-5 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Bixin is an orally active carotenoid found in the seeds of Bixa orellana. It is known for inducing apoptosis in cancer cells and possessing anti-inflammatory, anti-tumor, and anti-oxidant activities. Research indicates that Bixin treatment can ameliorate cardiac dysfunction by inhibiting fibrosis, inflammation, and reactive oxygen species (ROS) generation.
- Purity: 99.53%
- Molecular weight: 394.50; Formula: C25H30O4
- Appearance: Solid, brown to reddish brown
- Source: Bixa orellana seeds
- Induces apoptosis in cancer cells.
- Exhibits anti-inflammatory, anti-tumor, and anti-oxidant activities.
- Ameliorates cardiac dysfunction by inhibiting fibrosis, inflammation, and ROS generation.
- Attenuates inflammatory response via TLR4/NF-κB signaling pathway.
- Storage: 4°C (solid), -80°C (in solvent for 6 months), -20°C (in solvent for 1 month); protect from light.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC NI-57 | 1883548-89-7 | 99.4% | 383.42 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NI-57 is a chemical probe and an inhibitor of the bromodomain and plant homeodomain finger-containing (BRPF) family of proteins. It exhibits IC50s of 3.1, 46, and 140 nM for BRPF1, BRPF2 (BRD1), and BRPF3, respectively. It is intended for research use only and not for sale to patients.
- Inhibits BRPF family proteins with varying IC50s (3.1 nM for BRPF1, 46 nM for BRPF2 (BRD1), and 140 nM for BRPF3).
- Binds to the BRD of BRPF1 with a Kd of 31 ± 2 nM, BRD1 with a Kd of 110 ± 13 nM, and BRPF3 with a Kd of 410 ± 47 nM.
- Shows less activity on BRD9 (IC50, 520 nM) and BRD4 (BD1) (IC50, 3700 nM), and TRIM24 (IC50, 1600 nM).
- Inhibits BRPF BRDs in the nucleus.
- Reduces CCL-22 gene expression by 27.7 ± 9.4% at 10 μM.
- Has favorable oral bioavailability in mice.
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eMolecules Ambeed / 5-(25-Dimethylphenoxy)-22-dimethylpentanoic acid / 5g / 592283098 / A640007 / / 25812-30-0 / MFCD00079335 / 250.338 / C15H22O3
Ambeed / 5-(25-Dimethylphenoxy)-22-dimethylpentanoic acid / 5g / 592283098 / A640007 / / 25812-30-0 / MFCD00079335 / 250.338 / C15H22O3
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences Metaxalone United States Pharmacopeia (USP) Reference Standard | 1665-48-1 | MFCD00867700 | 200MG
Metaxalone United States Pharmacopeia (USP) Reference Standard | Mol Wt: 221.25 | 1665-48-1 | MFCD00867700 | 200MG
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eMolecules JW PharmLab LLC / 6-Methoxy-pyridine-3-sulfonyl chloride / 25g / 452546056 / 69R0147 / 97.000 / 312300-42-8 / MFCD06739108 / 207.630 / C6H6ClNO3S
JW PharmLab LLC / 6-Methoxy-pyridine-3-sulfonyl chloride / 25g / 452546056 / 69R0147 / 97.000 / 312300-42-8 / MFCD06739108 / 207.630 / C6H6ClNO3S
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules JW PharmLab LLC / Thiazole-4-carboxylic acid hydrazide / 25g / 452547866 / 90R0008 / 96.000 / 101257-38-9 / MFCD00614363 / 143.160 / C4H5N3OS
JW PharmLab LLC / Thiazole-4-carboxylic acid hydrazide / 25g / 452547866 / 90R0008 / 96.000 / 101257-38-9 / MFCD00614363 / 143.160 / C4H5N3OS
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / 4-Methoxy-1-naphthoic acid / 1g / 525135230 / A222787 / / 13041-62-8 / MFCD02575372 / 202.209 / C12H10O3
Ambeed / 4-Methoxy-1-naphthoic acid / 1g / 525135230 / A222787 / / 13041-62-8 / MFCD02575372 / 202.209 / C12H10O3
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Ambeed / 4-(1H-Pyrazol-1-yl)benzaldehyde / 250mg / 525046805 / A138603 / / 99662-34-7 / MFCD02681938 / 172.187 / C10H8N2O
Ambeed / 4-(1H-Pyrazol-1-yl)benzaldehyde / 250mg / 525046805 / A138603 / / 99662-34-7 / MFCD02681938 / 172.187 / C10H8N2O
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences [6]-Gingerol >=98% (HPLC) | 23513-14-6 | MFCD00210507 | 10MG
[6]-Gingerol >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 294.39 | 23513-14-6 | MFCD00210507 | 10MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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